Medications such as retatrutide, which affect multiple hormone pathways, GLP-1, GIP, and glucagon, could potentially provide quicker or more dramatic effects than single-pathway counterparts
The compounds cannot fully compensate for inadequate building blocks
One study of adults with severe obesity showed an average weight loss of 22.6%, or 55.8 pounds, after 80 weeks, while another study of adults with obesity and diabetes showed participants lost an average of 20.8% of their weight, or about 49.6 pounds
Discussion The three trials summarized in TABLE 2 provide consistent evidence that GLP-1 RAs may be an advantageous alternative to prandial insulin as add-on therapy to basal insulin
Consult qualified healthcare professionals for medical guidance
Biol Psychiatry 75:798806 King AC, Hasin D, OConnor SJ et al (2016) A prospective 5-year re-examination of alcohol response in heavy drinkers progressing in alcohol use disorder