This article systematically reviews the pathogenesis of NDs and the knowledge on curcumin including pharmacological effects, neuroprotective mechanisms, functions across specific NDs and advanced strategies to enhance the bioavailability, with the aim of promoting the development and clinical translation of curcumin-based therapeutics for NDs
2021 Sep;28(9):3100-3112
Ferroptosis in atherosclerosis Atherosclerosis is a long-term inflammatory condition marked by the development of lipid-rich plaques within large and medium-sized arteries, leading to diminished blood flow to tissues
Altogether, C3G was predicted as mh-Tyr alternative substrates which exhibit rapid oxidation, and hence, served as a weak competitive inhibitor by comparison to EC and CH compounds
Hydrogen provides antioxidant protection independent of NADPH status
Additionally, increased circulation and oxygen delivery to injured or damaged areas helps with cell turnover, reducing the appearance of scars