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Week-to-week fluctuations are normal and meaningless

Additionally, gastrointestinal side effectsnausea, constipation, or mild diarrheacan increase insensible fluid loss or discourage drinking when mild stomach discomfort is present

Freo U, Brugnatelli V, Turco F, Zanette G

Typical Clinical Trial Dosage Progression Gradual dose increases help the body adjust to the medication and may reduce gastrointestinal side effects

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