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This gene-regulatory capacity appears to be central to its observed effects, effectively recalibrating cellular activity towards a state of regeneration and homeostasis

Subsequently, we explored whether UBE2m regulated PPAR ubiquitination through NEDD4

Lancet (2017) 389(10080):174155

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For example, unlike bacterial or protozoal infections, which require 100% cure rates or risk relapse, reduction of worm burdens by 50% would lead to significant decreases in pathology and morbidity associated with schistosomiasis, and no rebound in pathology would occur because adult worms do not multiply in their host

Lemos Jnior et al., 2022