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Copper peptides (tripeptide glycyl-L-histidyl-L-lysine) are small fragments of proteins combined with a copper molecule with an affinity for skin cells, but can also be taken in tablet form to support copper defficiencies

Additional oral supplementation with polypodium leucotomos extract (PLE) at 480 mg twice daily can be helpful (anecdotal evidence, unpublished)

doi:10.1016/j.bbagen.2012.09.008

Oxidative Medicine and Cellular Longevity 2012:324832

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Research Context Potency: In preclinical studies, Dihexa was shown to be millions of times more potent than BDNF at stimulating synaptogenesis