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[4] Vegetarians/vegans: People who exclude meat from their diets are also at risk of iron deficiency because the iron in plant-based foods (non-heme iron) is harder for the body to absorb than the iron in animal products (heme iron)

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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy

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