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Phase 3 trials demonstrated that even doses two to three times higher than standard therapeutic levels caused manageable nausea and vomiting but not organ damage or mortality

Your provider can help determine if the itching is a minor irritation or if you need to switch to a different GLP-1 medication, such as tirzepatide (found in Mounjaro or Zepbound), which may be better tolerated by your skin

Overall adherence (kcals presented versus weighed back unconsumed food) was 94% (Table S3)

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[Abstract] Basic Clin Pharmacol Toxicol