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Tirzepatide is the only licenced GLP-1/GIP co-agonist for obesity, with several more GLP-1/GIP co-agonists in development [15]

Presuming that the putative high-folatelow-vitamin B-12 interaction on serum holoTC and the metabolic markers of vitamin B-12 status is due to excess folic acid, an important consideration is at what level of exposure might these effects become metabolically and clinically relevant

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Researchers continue to investigate these mechanisms within laboratory models of skin biology and tissue regeneration