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The ECS represents an important physiologic regulator of GI motility both centrally and peripherally

The Diabetes Prevention Programme trial showed that metformin reduced weight by approximately 23% of baseline body weight in individuals with prediabetes, which was less than lifestyle intervention alone

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IGF-1 LR3 is a different molecule, prescribed off-label by physicians and compounded by licensed pharmacies as part of wellness protocols

Notably, the frequency of these adverse events decreased overtime, and none were reported past Week 14

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