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Zozulya AA, Kost NV, Sokolov OY, et al

However, when combined with insulin or sulfonylureas, there is an increased risk of hypoglycaemia

Why Muscle Loss Drives Weight Regain Published body composition analyses suggest that a meaningful share of the weight lost during GLP-1 treatment can come from lean muscle tissue rather than adipose fat particularly when protein intake is insufficient and resistance exercise is not maintained