It has been reported to have a poor success rate to isolate very specific aptamer (67), leading to the development of in silico SELEX, a computational-based selection that can identify high affinity aptamer, shorten the aptamer selection process within an hour and provide additional information that can be retrieved such aptamer-protein binding site
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But we cant find a receptor, cant name a target, and cant find a gene for it in your genome is just giving up on science entirely
There is no trial that studied such a combination, which means anyone attempting it would be operating with zero efficacy evidence and stacked-up known risks
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(Cochrane Pregnancy and Childbirth Group) (January 2024)