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However, TMAO was found to increase ICAM-1 expression together with tumor necrosis factor (TNF)- and interleukin (IL)-6 in macrophages (Geng et al., 2018)
The general idea is that NAION occurs because cells begin to swell in the very tight space at the optic nerve head
Peptides act as signaling molecules, allowing cells to communicate and coordinate responses to environmental and metabolic changes
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26 As noted, this lesion also exhibits characteristics on imaging, such as dumbbell morphology, that are consistent with those of other spinal tumors, both benign and malignant, which may complicate its precise identification
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