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Inadequate skin preparation : Failing to properly clean and dry the application site is a frequent error

Skipping the starting dose significantly increases the risk of severe gastrointestinal side effects

Tirzepatide (Zepbound), a dual GLP-1/GIP agonist, is currently the FDA-approved weight loss drug with the highest efficacy

Microdosing is an alternative that involves taking a prescribed low dose

Eating smaller meals and drinking plenty of fluids can help mitigate this side effect

This trend is consistent with the pharmacological profile of retatrutide, which targets multiple hormonal pathways involved in the regulation of appetite and energy balance