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Yes, research has shown that vitamin C works well and can be used with other beneficial ingredients including niacinamide, retinol, peptides (except copper peptides, which Paulas Choice does not use) and exfoliating acids

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Yang XP, Reckelhoff JF

Evidence Tier Framework Tier 1 FDA-approved therapy large randomized trials Tier 2 human trials demonstrating biological effect Tier 3 small human studies or limited clinical data Tier 4 animal models or anecdotal reports Stacking should generally involve: at least one Tier 1 therapy no more than one Tier 3 compound Stacks composed entirely of Tier 34 compounds should not be considered clinical protocols

Understanding Liposomal Technology Liposomes are microscopic spherical vesicles composed of a phospholipid bilayer, similar to the structure of human cells

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