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Nature 475 , 106109 (2011)

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Key takeaways: The fetus cannot detoxify acetaminophen effectively and relies entirely on maternal metabolism

The key difference between l glutathione and S-Acetyl-L-glutathione is that l-glutathione is the abundant isomer form of glutathione, whereas S-Acetyl-L-glutathione is a derivative of glutathione

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These observed sex-dependent differences have been attributed to sex-dependent metabolic alterations such as the estrogen-dependent synthesis of phosphatidylcholines 88,89,90,91