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In some embodiments, the otoprotectant is a compound of Formula (XI) having the structure of Formula (XIa): In some embodiments, the otoprotectant is any one of the following compounds: or a pharmaceutically acceptable salt, pharmaceutically acceptable solvate or hydrate, pharmaceutically acceptable salt hydrate, or pharmaceutically acceptable prodrug thereof

Dietary supplements should be used as part of a healthy lifestyle and not as a substitute for a varied and balanced diet

Zepbound should not be used by individuals with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2

Brain Behav Immun 2013;30:15667

Pavik et al., 2013

Pernicious anemia is often found in conjunction with other autoimmune disorders, suggesting common autoimmune susceptibility genes may be a causative factor