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Compr Rev Food Sci Food Saf 17(3):556593

Notably, pro-inflammatory cytokines are also secreted by visceral adipose tissue in obesity and, together with the inhibition of IRS-1 mediated by TNF-, inhibition of c-Jun N-terminal kinase (JNK) and NK- B inhibitor, serve as major inflammatory mechanisms linking obesity with IR [75, 82]

low-density lipoprotein (LDL)

"Efficacy and safety of cagrilintide for weight management: A randomized phase 2 trial." Obesity , 31(3), 687-699

This occurs because the medication dramatically slows gastric emptying, which in turn slows the entire digestive transit

People who eat larger portions of protein-heavy or high-fat foods before their digestive system adapts may experience more pronounced symptoms