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Thom SR, Fisher D, Xu YA, Garner S, Ischiropoulos H

Khavinson VK, Bondarev IE, Butyugov AA

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Structural basis for GABAA receptor potentiation by neurosteroids

The rationale for titrating upward over time, rather than starting at the target dose, mirrors the approach taken with other metabolic peptides: the goal is to identify the minimum effective dose for each individual while monitoring for tolerability

About DSIP in research Researchers use DSIP in model systems to examine peptide-mediated signalling relevant to neuronal and cellular pathways, to profile downstream assay responses, and to compare structureactivity relationshipsexclusively in controlled, non-clinical in-vitro environments