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SGLT2 inhibitors, a related medication, were initially approved for diabetes, but then subsequently had indications added for heart failure and chronic kidney disease
MSH deficiency also causes early phase obesity and increases food intake and body weight [9]
Of course, combination comes on top, but if the monotherapy was not competitive, it would be hard to move it into Phase III. The oral GLP-1RA is far from the only obesity drug in AstraZenecas pipeline, said Sharon Barr, executive vice president of BioPharmaceuticals R&D at AstraZeneca
