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Short-acting GLP-1RAs, such as lixisenatide, maintain robust effects on gastric emptying, whereas long-acting agents, like liraglutide and semaglutide, exhibit reduced efficacy due to continuous receptor activation

Corinne at Legacy Physicians.

We comprehensively mapped the benefits and risks of GLP-1 receptor agonists (GLP-1) (Ozempic, Wegovy, Mounjaro, Zepbound)

This approach could potentially mitigate the loss of lean mass commonly seen with incretin therapies, a critical consideration for long-term metabolic health and physical function

24,25 The mechanisms of regulation and synthesis for GLP-1secretion are summarized in Figure 1

GLP-1 regulates gastroduodenal motility involving cholinergic pathways