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It depends on how bad the deficiency is and how well the person responds to treatment

Specific POPs have been associated with a higher risk for peripheral neuropathy among those with either impaired fasting glucose or diabetes, beyond the heightened risk due to diabetes itself

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Importantly, because GLP-1 receptor agonists work in a glucose-dependent manner, they generally carry a lower risk of hypoglycaemia compared to some other diabetes medications

In contrast, GLP-1 receptor agonists are particularly effective in reducing major adverse cardiovascular events, while their effect on HF hospitalization appears more modest, with relative risk reductions of approximately 11% (HR 0.89) in pooled analyses [6, 14]