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When circulating T 4 levels decrease, the pituitary gland increases its secretion of TSH, resulting in increased iodine trapping, as well as increased production and release of both T 3 and T 4
MDA levels remained constant throughout the storage in VC + VE, whereas decreased by 23% and 30% on days 14 and 42 respectively, in VC + NAC with day 1
In addition, ammonia impairs mitochondrial energy metabolism by inhibiting key enzymes of the tricarboxylic acid cycle, such as -ketoglutarate dehydrogenase, leading to ATP depletion [25]
doi: 10.3109/13590849609007262 154 PaciniSFioreMGMagheriniSMorucciGBrancaJJGulisanoMet al