[1] Brief bleeding at the injection site can occur normally and is not necessarily evidence of intravenous injection
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Combined with adequate protein intake (widely recommended at 1.2-1.6g per kg of body weight during GLP-1 protocols) and resistance training, the higher dose ranges may actually preserve lean mass better than lower doses, because the energy deficit is being met predominantly through fat oxidation rather than muscle catabolism
The FDA's warning emphasizes that semaglutide is contraindicated (should not be used) in patients with a personal history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2 (MEN2)
It often depends on the trigger, such as a large meal, and may subside after taking an antacid or once digestion has progressed
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