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It names rapid caloric restriction and delayed gastric emptying

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Ipamorelin and other growth hormone releasing peptides may also increase hunger, as its function mimics the function of ghrelin, the hunger hormone that increases appetite [13]

This is important because some absorption enhancers achieve their effects through mucosal damage, which is not acceptable for repeated administration

Interestingly, the researchers noted that combining the two forms resulted in less overall improvement than using them individually, suggesting a potential competition for intestinal absorption or cellular transport mechanisms