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Our functional and structural data, along with molecular dynamics (MD) simulations, suggest that receptor conformational dynamics associated with flexibility of the peptide N-terminal activation domain may be a key determinant of agonist efficacy

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In fact, they were more than twice as likely to lose at least 5% of their body weight

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doi: 10.1016/S0005-2760(97)00128-8 80 AisikuORRunnelsLWScarlataS

When the oxidative stress [which is defined as an imbalance that leads to cell and tissue damage] becomes too high in the body, then we start seeing all kinds of diseases: Obesity, diabetes, hypertension, heart disease, metabolic disorderswe can even go as far as cancer, he states