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In the perfusion studies, changes were evaluated based on either the mean incremental hormone output (subtraction of the preceding mean 5-minute baseline output from the mean stimulation period plus 5-minute poststimulation period, due to the often delayed response previously observed, ref

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Brcier A, Li VW, Smith CS, Halievski K, Ghasemlou N

This targeted protection effectively reduces membrane disruption and prevents mitochondrial dysfunction induced by oxidative stress [194]