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The synthetic triterpenoid CDDO-Me synergizes with midostaurin, avapritinib and nintedanib in counteracting growth and survival of neoplastic mast cells in advanced systemic mastocytosis

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As different classes of drugs target different aspects of T2DM via distinct mechanisms of action, a combination of treatments is generally more effective at maintaining glycaemic control than monotherapy over the long term [12]

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The other clearance mechanism available to the airway is coughing