Vitamin B12 is water-soluble, so excess amounts are generally excreted in the urine
doi:10.1210/jcem-70-4-975 Laferrre B, Abraham C, Russell CD, Bowers CY
The next most common abnormality is maternal disomy 15, found in around 35% of cases, and a defect in the imprinting center that controls the activity of certain genes on chromosome 15, seen in 1-3% of cases
The flushing often is accompanied by a burning sensation, particularly when creams or cosmetics are applied to the face
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Data extraction and risk of bias assessment Two researchers extracted data including the characteristics of the study population (number of patients per group, age, sex, diabetic status, liver disease status [NAFLD or NASH], and BMI per group), intervention(s) (TZD or GLP-1RA, treatment duration), control(s), outcome(s), and study results for each outcome according to a predefined Excel format
