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The two compounds in this category target complementary pathways of mitochondrial health: the NAD + activates sirtuins (SIRT1-7) and PARP-1 to restore energy metabolism and DNA repair, while the glutathione neutralizes reactive oxygen species generated by the mitochondrial respiratory chain

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Images were taken in phase contrast (a) or fluorescence for propidium iodide (b) and merged (c), under an epi-fluorescence microscope Zeiss Axio Imager Z1

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Discovery of small molecules targeting the growth hormone secretagogue receptor (GHS-R1a) for the treatment of obesity

Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX