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An enzyme in the taurine synthesis pathway, CDO1 limits cysteine accumulation by catalyzing the irreversible metabolism of cysteine to taurine synthesis precursors

Although significant progress has been made in buck semen cryopreservation techniques, critical challenges such as reduced post-thawing sperm motility, impaired sperm function, and oxidative stress remain unresolved [25]

The decreased NO activity and further deactivation by superoxide anion radical increase vascular resistance in renal arteries and manifest as hypertensive nephropathy and CVD [27].CKD patients have severe vitamin D deficiency that is further decreased by reduced activity of the enzyme 1- hydroxylase (CYP27B1), which converts 25-hydroxyvitamin D to its more active form, 1,25-dihydroxyvitamin D

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