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Although ACSL4 is consistently upregulated in OA cartilage and linked to ferroptosis progression, its inhibition must be balanced to avoid disrupting normal PUFA metabolism required for membrane integrity and repair (74, 77)

Vitamin B12 plays an important role in metabolism, energy production, and maintaining healthy cells

Ongoing investigations seek to fully characterize its effects and expand its applications in biomedical research

Even partial tears can lead to scapholunate advanced collapse (SLAC) wrist arthritis over time if the ligament does not heal properly