[4] [5] It's important to note that leptin resistance is not a formal clinical diagnosis with validated diagnostic criteria in UK practice, and routine leptin measurement is not recommended to guide therapy
[2] [7] These findings led regulatory authorities, including the Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMA), to include specific warnings and precautions in the prescribing information for all GLP-1 medications
Noble, G
The use of compounded drugs in patients using GLP-1s without medical supervision pose significant risk and can result in significant consequences, said Marina Basina, MD, a clinical professor in endocrinology, gerontology and metabolism
Van Ganse E, Laforest L, Pietri G, et al
Infrequently, allergic reactions or hormonal imbalances can occur