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GSTs as regulators of the MAP kinase pathway The first GST described was originally identified as ligandin due to its ability to interact covalently and noncovalently with various compounds that are not substrates for enzymatic activity, including steroids, thyroid hormones, bile acid, bilirubin, and heme (Litwack et al , 1971

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Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

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