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Deficiencies of B12 can manifest themselves as various symptoms

The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis

10.1016/s1474-4422(19)30320-5 Lancet Neurol

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Caffeine may also enhance endurance and strength by increasing fatty acid oxidation and sparing muscle glycogen [24]