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Originally developed as a therapy for type 2 diabetes, it is now widely used for weight management because of its effect on appetite regulation and glucose control

Oxidative stress is a shared characteristic of ME/CFS and Long COVID

However: Longer-term safety data (5+ years) is still being collected Individual risk factors vary significantly Regular medical monitoring essential for ongoing safety assessment Some individuals develop side effects requiring discontinuation Long-term cardiovascular benefits observed in some trials (SELECT trial with semaglutide) Healthcare providers should regularly reassess whether continued treatment remains appropriate for individual circumstances based on ongoing benefits, risks, and patient preferences

Advisory committee discussions or recommendations do not make a peptide FDA-approved and do not automatically authorize compounding

January 8, 2025

These cost differences highlight the need for direct head-to-head cost-effectiveness analyses to inform value-based prescribing between the two formulations