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Nanotechnology-mediated drug delivery can overcome several limitations of drugs, including insolubility, low bioavailability, fast metabolism, and poor stability

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These issues can lead to symptoms like: Bloating (especially after meals) Diarrhoea or constipation Excessive gas or frequent burping Nausea or feeling full quickly Abdominal pain or cramping Its estimated in people with IBS, SIBO may contribute to symptoms in around 38% of cases

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But patients were explicitly NOT told to attempt caloric restriction and instead eat according to their subjective hunger

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