10.2337/dci22-0027 Diabetes Care
The deciding factor in whether the molecule does anything visible on your face is whether it reaches the dermal fibroblast layer in functional quantity
If that inflammatory response is excessive, or if the skin is pushed too aggressively in a single session, the melanocytes respond by producing excess pigment
I am patiently waiting for future results
Although several natural compounds have entered preclinical or early clinical trials, the transition from bench to bedside is often hindered by limited pharmacokinetic stability, unclear mechanisms of action, and heterogeneous patient responses
Athauda D, Gulyani S, Karnati HK, et al