Six members voted against while one member abstained
Despite being the largest study in this field to date, covering more than 3.5 million pregnancies, relatively few women used the new diabetes drugs, and the researchers stress that further studies are needed to confirm the results
The adverse reactions, reported regardless of investigator assessment of causality in 5% of patients treated with Januvia 100 mg daily as monotherapy, Januvia in combination with pioglitazone, or Januvia in combination with glimepiride, with or without metformin, and more commonly than in patients treated with placebo, are shown in Table 1
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At the same time, Lillys established GLP-1 product Trulicity (dulaglutide) saw a 31% dip, pointing to some cannibalization by its newer offerings
A second phase 3 trial, SURMOUNT-2, enrolled patients with obesity or overweight with a comorbid diagnosis of type 2 diabetes