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On one hand, following colon entry, flavonoid metabolites display gut microbiota-dependent characteristics, such as equol, a metabolite derived from soy isoflavones, which forms entirely dependent on the presence and composition of gut microbiota (164, 165)
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In some embodiments, the otic formulation or composition comprises between about 0.10% to about 1% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof
It addresses the national discussion surrounding the GLP-1 medication shortage (e.g., Ozempic, Wegovy, Saxenda, Mounjaro, Zepbound) and alternative options like compounded formularies from 503A and 503B pharmacies.
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