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Bioinformatics analysis commenced with QIIME2-based OTU clustering, progressively advancing to -diversity (Shannon index) and -diversity assessments, ultimately employing Linear Discriminant Analysis (LDA) Effect Size (LEfSe) for differential taxon identification

For example, the review mentioned one study suggesting creatine may increase manic or hypomanic episodes in people with bipolar disorder and another linking just a week of 25 grams (g) daily supplements to increased nervousness and aggression in 2 out of 10 study participants

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The -oxidation ratio C0/(C16 + C18), a proxy for Carnitine Palmitoyltransferase I (CPT-I) activity, was significantly elevated in patients compared to healthy controls (34.55 14.88 vs

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