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6,20 Infants with G6PD deficiency and a mutation of uridine diphosphoglucuronate glucuronosyltransferase-1 gene promoter (UDPGT-1) are particularly susceptible to hyperbilirubinemia secondary to decreased liver clearance of bilirubin

However, for those who want to maintain normal eating patterns, avoid central appetite manipulation, or who cannot tolerate the gastrointestinal effects common with GLP-1 drugs, AOD-9604 offers an alternative mechanism

Vaduganathan M, Mensah George A, Turco Justine V, Fuster V, Roth GA

Theres a lot to consider before starting GLP-1s

doi: 10.3390/nu12051501 119

At the moment, the legal and regulatory framework remains unsettled