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The enzyme catalyzing these conjugations is glutathione S-transferase (GST) [47,60]

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Is autophagy associated with diabetes mellitus and its complications

Furthermore, in other disease models (such as A-induced nerve cell damage), highly expressed or activated VDAC1 has been clearly involved in ferroptosis, exacerbating cell death by inhibiting anti-ferroptosis pathways (such as GPX4, AMPK/mTOR, Wnt/-catenin) (149)