Intense interest in the TKTL1 gene, and its encoded protein, was stimulated because it was shown that the level of TKTL1 expression correlated with poor patient outcomes and metastasis in many solid tumors
(1) An interesting pathway in relation to this is the possibility of decreased levels of the antioxidant enzymes glutathione and paraoxonase, due to oxidative changes and cellular immunity at a genetically predisposed level
and if shelf life is 28 days, and I am to inject this into his subq once a week
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, Thompson CB
(B) Schematic representation of LMS-1 washing technique
Depriving tumours of extracellular glutathione or inhibiting its breakdown is potentially a viable therapeutic strategy for cancer patients, the authors state