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Immunofluorescence staining also showed a marked increase in the number of Ki-67-positive cells and a decrease in the nuclear content of -H2AX and P21 after FOXO4-DRI treatment (Figures 4B,C)

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The commenter stated that the ASC representative on the TEP did not support the use of the measure in the ASC setting and that ASC interested parties have not supported the measure in public comments