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10.1007/S00277-006-0205-2 81 LiuJ

Injectable reactive oxygen species-responsive hydrogel dressing with sustained nitric oxide release for bacterial ablation and wound healing

However, starting with an SGLT2 inhibitor or a GLP-1 RA in an individual who is intolerant to metformin (primarily diarrhea) is a good choice, and even in the future we may see large diabetes organizations recommending these two classes as first line therapy once they get less expensive.

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Bottom line: A healthy gut requires a multi-faceted approach