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These outcomes are hypothesized on the basis of the known biology of the GH/IGF-1 axis and must be framed accordingly: All outcome claims should be interpreted strictly within a hypothesized or investigator-reported framework, not as established therapeutic effects

STF-31 is a small-molecule inhibitor of NAMPT that selectively kills renal cell carcinoma cells upon the loss of the von Hippel-Lindau (VHL) tumor suppressor gene