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Traditional treatment approaches often fall short

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From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models

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terminal half-life 20-50 minutes) with a steady-state volume approximating total extracellular fluid, findings that justify loading schedules followed by less frequent injections once tissue stores exceed 2 mg

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