Cortisol production normally follows a diurnal (daily) pattern, with higher levels in the morning and lower levels at night
Rubino, 2015
Finding the Right Balance for Your Goals If your primary goal is general wellness and healthy ageing, a lower daily dose of both may be sufficient
In addition, SFN treatment ameliorated colon and caecal mucosal epithelial damage in mice with N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced bladder cancer through up-regulation of tight junction protein expression, downregulation of IL-6 release, and prevention of gut dysbiosis (He et al., 2018)
Build muscle or improve athletic performance: Along with regular strength training, consider taking a creatine supplement
Pharmaceuticals can deplete essential nutrients at any time depending on your original nutrient status, so just because your vitamins and minerals are balanced one month doesnt mean theyll stay that way