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Similarly, studies on oxidative stress in skin conditions support the idea that antioxidants could play a beneficial role in preserving cellular integrity (Bickers & Athar, 2006)

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The level of TMAO was significantly positively correlated with the incidence of calcification in the intimal lesion (25)

Its antioxidant properties reduce oxidative stress that leads to acne and inflammation

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Moreover, the diabetic db/db mice exhibited significantly higher TMAO concentrations, increased body weight, and insulin resistance compared to non-diabetic db/L mice, demonstrating that diabetes and BMI are positively related to circulating TMAO levels (Miao et al