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Once the patient has ramped up, they generally stay on the same dose (typically 1.0 mg) for an extended period of time

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24,51 In venous umbilical cord blood, the lower methionine/homocysteine ratio in severe IPTB, compared with moderate IPTB, suggests impaired remethylation, favoring H 2 S biogenesis over demethylation and transsulfuration (Fig

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